Semax / Selank dosage chart
This summary compares component doses by route. These are separate component amounts, not a combined blend dose.
Semax / Selank dosage by administration route
Semax · Intranasal
Reported intranasal protocols use 300–600 mcg per day, divided across 1-2 administrations daily for 4-12 weeks.[7][1][8]
Semax is an ACTH-fragment analogue associated with neurotrophic and stress-response signaling. Nasal formulations have their own concentrations and delivery volumes.[1][8][9]
Semax · Injectable
Reported-use amounts for Semax are ~300 mcg per administration, daily, for 4–12 wk. Another reported once-daily subcutaneous progression uses 200 mcg in weeks 1–2, 300 mcg in weeks 3–4, 400 mcg in weeks 5–6 and 500 mcg in weeks 7–12. The same source also lists a separate 6–8-week course followed by 2–4 weeks off; these are not nasal-product directions.[16][17]
Injectable Semax is a separate preparation of the ACTH-fragment analogue. Nasal concentration and spray volume do not define an injectable amount.[1][8][9][16]
Selank · Intranasal
Reported intranasal protocols use 250–400 mcg per day, divided across 1-2 administrations daily for 2-6 weeks.[14][3][4]
Selank is a tuftsin-derived peptide associated with anxiety and stress-response signaling. Nasal concentration and the volume delivered per application determine the actual amount.[3][4][15]
Selank · Injectable
Reported-use amounts for Selank are ~250 mcg per administration, daily, for 2–6 wk. A reported subcutaneous progression uses 300 mcg once daily for weeks 1–2 and 500 mcg once daily for weeks 3–4, followed by four weeks off. This four-week-on/four-week-off pattern is not a nasal formulation schedule.[16][18]
Injectable Selank is a separate preparation of the tuftsin-derived peptide. Nasal concentration and delivered spray volume do not define its injection amount.[3][4][15][16]
Frequency and timing
Semax: Morning or afternoon is the listed timing for the nasal and injection patterns.[7][1][8][16]
Selank: Afternoon or evening is the listed timing for the nasal and injection patterns.[14][3][4][16]
Cycle length and breaks
Semax: Intranasal: 4-12 weeks. Injectable: 4–12 wk. A separate reported subcutaneous cycle pattern uses 6–8 weeks on, followed by 2–4 weeks off; nasal schedules differ.[7][1][8][16][17]
Selank: Intranasal: 2-6 weeks. Injectable: 2–6 wk. A separate reported subcutaneous cycle pattern uses four weeks on followed by four weeks off; nasal schedules differ.[14][3][4][16][18]
Semax / Selank dosage calculator
Calculate each separately prepared component using its own vial strength and final volume. A fixed-ratio blend requires the amount of every component; the total blend weight alone is insufficient.
See the reconstitution guidelines for preparation terms. For the distinction between separate preparations and mixed vials, read the mixing versus co-scheduling explainer.
Semax / Selank safety and side effects
Combination and product quality
A standardized combined Semax and Selank regimen is not established. Spray concentration and delivered volume determine each component amount. Headache, irritability, anxiety and sleep changes can overlap with effects from caffeine, stimulants and other neuroactive medicines.[2][4][3][6]
Side effects and long-term safety
Semax: Nasal irritation, headache, sleep disruption and overstimulation are practical tolerability concerns. Long-term repeated intranasal use, interactions, pregnancy and pediatric safety remain poorly characterized.[1][8][9][10]
Selank: Nasal irritation, fatigue, headache and calm or sedating effects are practical tolerability concerns. Long-term intranasal use, medication interactions, pregnancy and pediatric safety remain poorly characterized.[3][4][15][5]
Route-specific dosing limits
Separate products and fixed-ratio blends have different preparation requirements. Keep the exact formulation, component amount and route with each recorded dose. Reported-use schedules for Semax (injectable) and Selank (injectable) are not established human treatment regimens.[16][17][18]
Peptides in Semax / Selank
Open each full dosage guide for its routes, schedules and references.
Common Semax / Selank dosage questions
Does Semax / Selank have one combined dose?
Each component has its own amount and schedule. A stack name does not define a blend ratio or combined dose.
Can the component doses be calculated separately?
Yes, for separately prepared components. Use each vial's peptide amount and final volume in the calculator. A combined vial requires its exact component composition.
Does one spray always represent the same dose?
What cycle and break patterns are listed for the components?
Semax: Intranasal: 4-12 weeks. Injectable: 4–12 wk. A separate reported subcutaneous cycle pattern uses 6–8 weeks on, followed by 2–4 weeks off; nasal schedules differ.[7][1][8][16][17]
Selank: Intranasal: 2-6 weeks. Injectable: 2–6 wk. A separate reported subcutaneous cycle pattern uses four weeks on followed by four weeks off; nasal schedules differ.[14][3][4][16][18]


