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Sermorelin dosage

Compare Sermorelin injection progressions with nasal-spray schedules, keeping vial amounts and per-spray strengths distinct. Calculate volume and syringe units using your own vial inputs.

Full Sermorelin library reference

Sermorelin dosage chart

This summary table compares available dose amounts and schedules by administration route.

RouteDoseFrequency & duration
Injectable0.2–0.5 mgDaily · 3-6 months
Intranasal~100 mcg / spray5 nights / wk · Ongoing

Sermorelin dosage by administration route

Sermorelin injectable dosage

Reported injectable protocols use 0.2–0.5 mg per administration, daily for 3-6 months. A reported bedtime progression uses 200 mcg in weeks 1–2, 300 mcg in weeks 3–4, 400 mcg in weeks 5–6 and 500 mcg from week 7. An alternative schedule uses a 3–6-month course; these are reported subcutaneous steps rather than nasal-spray directions.[1][2][8][9][3][4][5][11]

Sermorelin is a GHRH(1–29) analogue that stimulates pituitary GH secretion. Response depends on the underlying endocrine condition and pituitary function.[1][2][6]

Sermorelin intranasal dosage

Reported-use amounts for Sermorelin are ~100 mcg / spray, 5 nights / wk, on an ongoing basis.[10]

Nasal sermorelin is a formulation of the GHRH(1–29) analogue. Its delivered amount depends on the concentration and volume per spray, separately from an injection preparation.[7][2][6][1][10]

Frequency and timing

The injection pattern is timed before bed. The nasal pattern also lists bedtime use on five nights per week.[3][8][9][1][2][4][5][10]

Cycle length and breaks

Injectable: 3-6 months. Intranasal: Ongoing. Ongoing treatment does not follow a routine on/off cycle.[1][2][8][9][3][4][5][10]

Sermorelin dosage calculator

Convert your chosen Sermorelin amount into volume and U-100 syringe units. Adjust the inputs to match your vial and preparation.

Sermorelin dosage calculator

Calculate concentration, draw units and total doses.

mg
mg
mL
Concentration
2.5mg/mL
Draw units
8units
Total doses
25
Volume per dose
0.08mL
Daily amount
0.2mg
Complete days per vial
25
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Sermorelin safety and side effects

Approval and product quality

Sermorelin is not an FDA-approved drug.[2]

Side effects and long-term safety

Local injection tolerance, flushing, headache, water retention and glucose or IGF-1 effects are relevant concerns. Pregnancy, active malignancy and sports restrictions also require attention.[2][1]

Route-specific dosing limits

Long-term unapproved GH-secretagogue use needs lab monitoring and careful exclusion of higher-risk contexts. Reported-use intranasal schedules and additional protocol patterns are not established human treatment regimens or approved product instructions.[2][1][11][10]

Common Sermorelin dosage questions

Can Sermorelin doses be transferred between routes?

No. Each route and formulation has its own exposure and administration requirements. Use the dose information for the exact presentation rather than copying a tablet, injection or local-product amount to another route.[1][2][7]

What dosage is listed for Sermorelin?

Reported injectable protocols use 0.2–0.5 mg per administration, daily for 3-6 months.[1][2][8][9][3][4][5][11]

Does Sermorelin have a standard cycle or break interval?

Injectable: 3-6 months. Intranasal: Ongoing. Ongoing treatment does not follow a routine on/off cycle.[1][2][8][9][3][4][5][10]

Sources

Show citationsHide citations
[1]Once daily subcutaneous growth hormone-releasing hormone therapy accelerates growth in growth hormone-deficient children during the first year of therapy. Geref International Study Group.The Journal of clinical endocrinology and metabolism, 1996 Mar. human clinical.[2]Search Drugs@FDA for sermorelin acetate / GerefU.S. Food and Drug Administration / openFDA. database query.[3]Testing with growth hormone-releasing factor (GRF(1-29)NH2) and somatomedin C measurements for the evaluation of growth hormone deficiency.European journal of pediatrics, 1986 Dec. review.[4]Sermorelin: a better approach to management of adult-onset growth hormone insufficiency?Clinical interventions in aging, 2006. review.[5]Beyond the androgen receptor: the role of growth hormone secretagogues in the modern management of body composition in hypogonadal males.Translational andrology and urology, 2020 Mar. review.[6]Sermorelin: a review of its use in the diagnosis and treatment of children with idiopathic growth hormone deficiency.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy, 1999 Aug. review.[7]The effects of intranasal insufflation of growth hormone releasing factor analogue GRF 1-29 NH2 on growth hormone secretion in children with short stature.Acta endocrinologica. Supplementum, 1986. review.[8]Commonly prescribed compounds: Sermorelin nasal spray 100 mcg per sprayVertisis Custom Pharmacy, 2022 Aug. reference catalog.[9]Sermorelin provider guide: compounded formulations and dosingStrive Pharmacy. reference catalog.[10]PepFlow peptide cheat sheet — reported-use and product-orientation reference (not clinical research)PepFlow. reference catalog.[11]Sermorelin — Everything Peptide reported protocol (educational reference, not clinical evidence)Everything Peptide. reference catalog.

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