Melanotan I dosage chart
This summary table compares available dose amounts and schedules by administration route.
| Route | Dose | Frequency & duration |
|---|---|---|
| Subcutaneous | 16 mg implant | Every 2 months · Ongoing |
Melanotan I dosage by administration route
Melanotan I subcutaneous implant dosage
For adults with erythropoietic protoporphyria, the SCENESSE (afamelanotide) dose is one 16 mg subcutaneous implant every 2 months.[1]
Afamelanotide activates melanocortin-1 receptors and increases eumelanin production. SCENESSE may support tolerance of light exposure in adults with erythropoietic protoporphyria.[2][3][4]
Cycle length and breaks
Subcutaneous implant: Ongoing. Ongoing treatment does not follow a routine on/off cycle.[1]
Melanotan I dosage calculator
Convert your chosen Melanotan I amount into volume and U-100 syringe units. Adjust the inputs to match your vial and preparation.
Melanotan I safety and side effects
Approval and product quality
SCENESSE afamelanotide implant is FDA-approved for erythropoietic protoporphyria photoprotection; cosmetic tanning products or self-injected Melanotan I are separate.[1][5]
Side effects and long-term safety
The clearest tolerability signals come from the afamelanotide implant label context. Cosmetic tanning protocols and self-injected products are separate from the SCENESSE EPP label and have different safety uncertainty. Melanotan I safety should separate SCENESSE implant labeling for EPP from non-label tanning use. Skin monitoring, implant-site reactions, nausea, fatigue, and pigmentation matter.[1][2]
Common Melanotan I dosage questions
What dosage is listed for Melanotan I?
For adults with erythropoietic protoporphyria, the SCENESSE (afamelanotide) dose is one 16 mg subcutaneous implant every 2 months.[1]
Does Melanotan I have a standard cycle or break interval?
Subcutaneous implant: Ongoing. Ongoing treatment does not follow a routine on/off cycle.[1]


