hCG dosage chart
This summary table compares available dose amounts and schedules by administration route.
| Route | Dose | Frequency & duration |
|---|---|---|
| Intramuscular | 500–1,000 USP units (male hypogonadotropic hypogonadism) | 3 times weekly for 3 weeks, then twice weekly · 6 weeks |
| Intramuscular | 5,000–10,000 USP units (ovulation induction) | Single dose · One day after the last menotropin dose |
| Sublingual | 200 IU (compounded fertility tablet) | Once daily · Late follicular phase; begins at a 14 mm follicle |
| Intrauterine | 500 IU in 0.1 mL | Single administration · 4 minutes before embryo transfer |
hCG dosage by administration route
hCG injectable dosage
For male hypogonadotropic hypogonadism, labeled Pregnyl regimens include 500–1,000 USP units intramuscularly three times weekly for 3 weeks, followed by twice weekly for 3 weeks. For ovulation induction, the label gives a single 5,000–10,000 USP unit intramuscular dose on the day after the last menotropin dose. A reported schedule uses 250–500 IU two or three times weekly during testosterone therapy, and a separate 500–1,000 IU daily post-cycle pattern. These contexts differ from labeled hypogonadotropic hypogonadism and ovulation-induction regimens; the source does not establish an approved post-cycle protocol.[1][2][10]
hCG activates the LH/CG receptor. Its effects on ovulation and testicular hormone production require indication-specific regimens.[1][3][4]
hCG sublingual — compounded tablet; fertility trial dosage
A compounded sublingual hCG tablet schedule uses 200 IU daily alongside clomiphene or letrozole for ovulation induction, beginning when the largest follicle reaches 14 mm on ultrasound. The protocol follows follicular development rather than a fixed number of days. No significant improvement in ovulation induction was demonstrated; this preparation is unrelated to weight-loss drops.[7]
This formulation was evaluated as an adjunct in monitored fertility care. The small trial did not demonstrate a significant improvement in ovulation induction.[7][1][3][4]
hCG intrauterine dosage
A documented investigational IVF procedure uses 500 IU in 0.1 mL culture medium, administered into the uterus four minutes before embryo transfer. This is a fertility-clinic procedure, separate from an ovulation-trigger injection; a benefit over control was not established.[8]
Local intrauterine hCG is administered as part of an embryo-transfer procedure. Its formulation and purpose are distinct from systemic ovulation-trigger injections and testicular hormone treatment.[8][1][3][4]
hCG dosage calculator
Convert your chosen hCG amount into volume and U-100 syringe units. Adjust the inputs to match your vial and preparation.
hCG safety and side effects
Approval and product quality
FDA-approved chorionic gonadotropin products have reproductive-endocrine indications; weight-loss, bodybuilding, or casual hormone-support use is outside those labels.[1][6]
Side effects and long-term safety
Injection reactions, headache, mood symptoms, edema, ovarian hyperstimulation syndrome (OHSS), gynecomastia and thromboembolism are relevant adverse effects. Risk depends on the reproductive-endocrine indication.[1][3][4][9]
Route-specific dosing limits
Ovarian stimulation, estradiol response and clot risk require indication-specific care. Sports restrictions and non-medical weight-loss, performance or casual hormone-support use are separate considerations from reproductive care. Additional schedules attributed to Everything Peptide are reported patterns; citing research does not make these schedules clinically established or approved product instructions.[1][3][4][9][10]
