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GHRP-6 dosage

Compare GHRP-6 injection, oral, nasal and sublingual amounts with transdermal delivery preparations. Calculate volume and syringe units using your own vial inputs.

Full GHRP-6 library reference

GHRP-6 dosage chart

This summary table compares available dose amounts and schedules by administration route.

RouteDoseFrequency & duration
Oral0.3 mg/kg2x daily · 4 days
Injectable100–300 mcg2-3 times daily · 8-12 weeks
Intranasal0.03 mg/kgSingle dose · Single dose
Transdermal75.3 mcg/cm² loaded (800 µm array); 42.8 mcg/cm² (500 µm array)Single laboratory exposure · 24-hour release measurement
Sublingual30 mcg/kgSingle evening administration · Single night

GHRP-6 dosage by administration route

GHRP-6 oral dosage

Reported-use amounts for GHRP-6 are 0.3 mg/kg, 2x daily, for 4 days.[11]

GHRP-6 is a ghrelin-receptor agonist with GH-release and appetite effects. Appetite stimulation can be a relevant response alongside endocrine activity.[1][2][3][4][11]

GHRP-6 injectable dosage

Reported injectable protocols use 100–300 mcg per administration, 2-3 times daily for 8-12 weeks. An additional reported subcutaneous pattern uses 100–200 mcg per administration one to three times daily for 8–12 weeks. Amount per administration and total daily amount should remain separate when comparing frequencies.[2][3][5][10][6][1][12]

GHRP-6 is a ghrelin-receptor agonist with GH-release and appetite effects. Appetite stimulation can be a relevant response alongside endocrine activity.[2][3][5][4]

GHRP-6 intranasal dosage

Reported-use amounts for GHRP-6 are 0.03 mg/kg, as a single dose.[11]

GHRP-6 is a ghrelin-receptor agonist with GH-release and appetite effects. Appetite stimulation can be a relevant response alongside endocrine activity.[6][2][3][4][11]

GHRP-6 transdermal — ex vivo dissolving microneedles dosage

Dissolving PVA/PVP microneedle arrays carry 75.3 mcg/cm² of GHRP-6 with 800-micrometer needles or 42.8 mcg/cm² with 500-micrometer needles. Release is measured across excised pig skin over 24 hours. These figures describe the peptide loaded onto each skin area, not a measured human absorbed dose.[7][13]

The PVA/PVP arrays dissolve after insertion into the skin sample. Only part of the peptide used during casting remains in the finished microneedles; the initial 2.5 mg casting input is not the final patch payload.[7][2][3][4]

GHRP-6 sublingual dosage

A documented investigational sublingual amount is 30 mcg/kg as a single evening administration. A repeat course is not established, and the endocrine response was limited to a trend rather than a confirmed treatment effect.[6]

GHRP-6 is a ghrelin-receptor agonist with GH-release and appetite effects. Appetite stimulation can be a relevant response alongside endocrine activity.[6][2][3][4]

Frequency and timing

The oral and nasal patterns list pre-meal timing. Injections are commonly timed in the morning, before a workout or before bed. The sublingual exposure is a single evening administration; the experimental transdermal preparation follows its own laboratory schedule.[2][3][5][10][6][1][11][7][13]

Cycle length and breaks

Oral: 4 days. Injectable: 8-12 weeks. Intranasal: Single dose. Transdermal — ex vivo dissolving microneedles: 24-hour release measurement. Sublingual: Single night. A standard break interval between courses is not established.[11][2][3][5][10][6][1][7][13]

GHRP-6 dosage calculator

Convert your chosen GHRP-6 amount into volume and U-100 syringe units. Adjust the inputs to match your vial and preparation.

GHRP-6 dosage calculator

Calculate concentration, draw units and total doses.

mcg
mg
mL
Concentration
1.66667mg/mL
Draw units
6units
Total doses
50
Volume per dose
0.06mL
Daily amount
200mcg
Complete days per vial
25
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GHRP-6 safety and side effects

Approval and product quality

GHRP-6 is not an FDA-approved drug.[8][9]

Side effects and long-term safety

Hunger, water retention, glucose and IGF-1 changes, and ACTH, cortisol or prolactin effects are relevant to ghrelin-receptor and GH-axis stimulation. Injectable product quality, pregnancy, active malignancy and sports restrictions also require attention.[2][3][5][8][9]

Route-specific dosing limits

Long-term unapproved GH-secretagogue use needs lab monitoring and careful exclusion of higher-risk contexts. Reported-use oral and intranasal schedules and additional protocol patterns are not established human treatment regimens or approved product instructions.[2][3][5][8][9][12][11]

Common GHRP-6 dosage questions

Can GHRP-6 doses be transferred between routes?

No. Each route and formulation has its own exposure and administration requirements. Use the dose information for the exact presentation rather than copying a tablet, injection or local-product amount to another route.[1][2][3][5][10][7][6]

What dosage is listed for GHRP-6?

Reported-use amounts for GHRP-6 are 0.3 mg/kg, 2x daily, for 4 days.[11]

Does GHRP-6 have a standard cycle or break interval?

Oral: 4 days. Injectable: 8-12 weeks. Intranasal: Single dose. Transdermal — ex vivo dissolving microneedles: 24-hour release measurement. Sublingual: Single night. A standard break interval between courses is not established.[11][2][3][5][10][6][1][7][13]

Sources

Show citationsHide citations
[1]Growth hormone-releasing activity of growth hormone-releasing peptide-6 is maintained after short-term oral pretreatment with the hexapeptide in normal agingEuropean Journal of Endocrinology, 1994-11. human clinical.[2]Pharmacokinetic study of Growth Hormone-Releasing Peptide 6 (GHRP-6) in nine male healthy volunteers.European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2013 Jan 23. human clinical.[3]Effects of ghrelin, growth hormone-releasing peptide-6, and growth hormone-releasing hormone on growth hormone, adrenocorticotropic hormone, and cortisol release in type 1 diabetes mellitus.Metabolism: clinical and experimental, 2010 Oct. human clinical.[4]Growth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation.The Journal of clinical endocrinology and metabolism, 1998 Apr. human clinical.[5]Effects of ghrelin, GH-releasing peptide-6 (GHRP-6) and GHRH on GH, ACTH and cortisol release in hyperthyroidism before and after treatment.Pituitary, 2010 Dec. human clinical.[6]Effects of growth hormone-releasing peptide-6 on the nocturnal secretion of GH, ACTH and cortisol and on the sleep EEG in man: role of routes of administration.J Neuroendocrinol, 1999 Jun. human clinical.[7]A quantitative UHPLC-MS/MS method for the growth hormone-releasing peptide-6 determination in complex biological matrices and transdermal formulations.Talanta, 2021 Oct 01. ex vivo.[8]Search Drugs@FDA for GHRP-6U.S. Food and Drug Administration / openFDA. database query.[9]United Pharmacy MARCS-CMS 553916 - February 11, 2019U.S. Food and Drug Administration, 2019-02-11. regulatory.[10]Intranasal Administration of Growth Hormone Releasing Peptide Increased Plasma Growth Hormone and Insulin-like Growth Factor-I Levels in Normal MenEndocrinologia Japonica, 1991. human clinical.[11]PepFlow peptide cheat sheet — reported-use and product-orientation reference (not clinical research)PepFlow. reference catalog.[12]GHRP-6 — Everything Peptide reported protocol (educational reference, not clinical evidence)Everything Peptide. reference catalog.[13]Développement de nouveaux systèmes de délivrance de substances actives administrées par la voie transcutanée — GHRP-6 microneedle methods and loadingCloé Esposito / Université de Montréal (2021 doctoral thesis). ex vivo.

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